If your dog could talk, the first thing they’d ask for after a walk might just be “those yummy mushroom cookies that make my hips feel like a puppy again.”
That’s the magic behind the newest wave of canine wellness: soft-chew treats that pair hemp-derived CBD with functional fungi—think reishi for calm, lion’s mane for cognition, and turkey tail for immunity. Veterinarians, herbalists, and everyday pet parents are suddenly speaking the same language, and it’s spelled in three letters: C-B-D. But before you add anything to your pup’s bowl, it pays to separate the science from the hype and learn what actually matters when you’re shopping for holistic hound CBD mushroom treats in 2025.
Top 10 Holistic Hound Cbd Dog Treats
Detailed Product Reviews
1. Thrivin Tails Bacon-Flavored Calming Chews for Dogs: Hemp and Melatonin Dog Anxiety Relief Treats, CBD-Infused Calming Chews and Treats for Dogs, Perfect Sleep Aid, 120 Count
Overview: Thrivin Tails Bacon-Flavored Calming Chews combine CBD and melatonin in a tasty bacon package to ease canine anxiety and promote restful sleep. Each 120-count bottle delivers gentle, hemp-based relaxation for dogs facing stress from thunderstorms, separation, or bedtime hyperactivity.
What Makes It Stand Out: The dual-action CBD + melatonin formula is rare at this price, and the bacon flavor makes administration effortless—most dogs think it’s a high-value treat. The brand also emphasizes clear dosing instructions, reducing guesswork for owners.
Value for Money: At $0.22 per chew, you’re paying a slight premium over plain-herbal competitors, but the inclusion of CBD and melatonin justifies the uptick. One bottle lasts a 30-lb dog four months when used daily, translating to about $6.50 a month for multi-modal calm.
Strengths and Weaknesses: Strengths: palatability is off the charts, sleep support is noticeable within 45 min, and the hemp extract is THC-free. Weaknesses: CBD levels aren’t disclosed per chew, so precise mg dosing is impossible; not ideal for pregnant or breeding dogs; bacon aroma can linger on hands.
Bottom Line: If your dog needs nighttime serenity or storm-time stillness and you’re comfortable with hemp, Thrivin Tails is a flavorful, mid-priced option worth keeping on the shelf.
2. Calming Chews for Dogs – Advanced Hemp Dog Calming Treats Help with Dog Anxiety Relief, Separation, Stress, Barking, Fireworks, Composure – Natural Pet Supplements for Health & Wellness 180 Soft Chews
Overview: These Advanced Hemp Calming Treats cram 180 chicken-flavored soft chews into one tub, using chamomile, L-theanine, valerian, and magnesium to curb barking, fireworks freak-outs, and vet-visit jitters without sedation.
What Makes It Stand Out: The formula skips hemp extract in favor of proven amino acids and herbs, so you get anti-anxiety benefits without CBD legal grey areas. Thirty-minute onset and a generous 180-count make it a practical staple for multi-dog households.
Value for Money: $0.14 per chew is among the lowest in the calming category—cheaper than a daily dental stick yet packed with active botanicals. One tub covers a 50-lb dog for six months of situational use.
Strengths and Weaknesses: Strengths: fast-acting, non-drowsy, universally tasty chicken flavor, and dosage chart for every size from teacup to mastiff. Weaknesses: strong herbal smell, not chicken-like to human noses; large breeds need 3–4 chews per event, so heavy users burn through supply quickly.
Bottom Line: For owners who want reliable, CBD-free calm on a budget, these chews deliver solid results and unbeatable cost-per-dose.
3. Hemp Calming Chews for Dogs – Advanced Dog Calming Treats Helps with Dog Anxiety Relief, Separation, Stress, Barking, Fireworks, Travel, Composure – Natural Pet Supplements for Health & Wellness 180Ct
Overview: Nearly identical in formula to Product 2, this 180-count Hemp Calming offering blends magnesium citrate, chamomile, L-tryptophan, L-theanine, valerian, and ginger into a chicken soft chew marketed for travel, fireworks, and separation stress.
What Makes It Stand Out: The manufacturer undercuts its own sibling SKU by one dollar while keeping the same ingredient deck, creating an even lower cost-per-chew. Resealable tub preserves softness in humid climates.
Value for Money: At $23.99 for 180 chews ($0.13 each), it’s the cheapest herbal calming bite we’ve seen—basically bulk-bin pricing with human-grade botanicals. A 25-lb dog needing storm-season support gets three months of daily calm for under eight bucks.
Strengths and Weaknesses: Strengths: price king, non-CBD formula keeps TSA and landlords happy, ginger aids sensitive stomachs during car rides. Weaknesses: identical copy-paste marketing creates consumer confusion; some lots arrive overly soft and stick together in summer heat.
Bottom Line: If your sole metric is pennies per calm, this tub wins—just store it in a cool cabinet and double-check you’re ordering the version you intended.
4. GOODGROWLIES Advanced Calming Chews for Dogs – Hemp Treat + Melatonin + Valerian – Relaxing Bites – Calming Care – Anti-Anxiety & Stress Relief – Made in USA – Calm, Sleep Aid, Storms – 120Ct
Overview: GOODGROWLIES packs 120 USA-made soft chews with hemp, melatonin, and valerian to act as both daily anti-anxiety supplement and bedtime sleep aid. The gummy-like texture replaces hard-to-swallow pills for dogs averse to tablets.
What Makes It Stand Out: The inclusion of melatonin alongside hemp differentiates it from purely herbal competitors, offering drowsy-free daytime calm yet extra nudge toward sleep when given in the evening. “No risk, just results” guarantee promises a refund if your pup stays wired.
Value for Money: Mid-range $0.21 per chew feels fair for a dual-purpose hemp + melatonin product made stateside. A 40-lb dog on maintenance dosing finishes the jar in 60 days, costing roughly twelve dollars monthly—less than a coffee habit.
Strengths and Weaknesses: Strengths: noticeable sedative edge without prescription drugs, soft texture suits seniors with dental issues, clear melatonin content listed. Weaknesses: duck-like smell is off-putting to picky eaters, 120-count runs out fast for giant breeds, hemp source certificate only available on request.
Bottom Line: Owners who need a trustworthy USA-made calm-and-sleep chew will find GOODGROWLIES a balanced, if slightly aromatic, choice backed by a money-back promise.
5. Hemp Calming Chews for Dogs Anxiety Relief – Dog Calming Treats with Melatonin, Chamomile Extract, Valerian Root – Travel Pack – Anxiety Relief Chews for Vet Visits, Grooming, Nail Trimming, Storms
Overview: This travel-pouch of Hemp Calming Chews targets on-the-go stress—vet visits, grooming, nail trims—with a wallet-friendly 60-count sleeve infused with L-theanine, hemp seed oil, chamomile, and valerian root. Resealable zip-lock keeps chews fresh in glove boxes and handbags.
What Makes It Stand Out: The $9.49 price tag is impulse-buy territory, yet the formula still covers amino acids, herbs, and omega-rich hemp seed oil. Portability is the star: slim pouch slips into a purse better than bulky tubs.
Value for Money: At $0.14 per chew you’re paying the same low rate as bulk jars but without the upfront commitment. Perfect for testing effectiveness or occasional use without 180-chew overkill.
Strengths and Weaknesses: Strengths: ultra-portable, single-hand zip closure, no CBD so no state-restriction worries, mild cheese aroma appeals to finicky dogs. Weaknesses: only 60 chews means heavy users reorder often; softer texture can crumble underfoot if pouch gets crushed in a backpack.
Bottom Line: For trial runs, road trips, or tiny-dog households, this pouch offers high-powered calm at pocket-change pricing—just buy two if your hound is over 60 lbs.
6. STRELLALAB Hemp Calming Chews for Dogs – Melatonin Dog Treats – Anxiety Relief – Calming Chews – Sleep & Stress Aid for Separation – 120ct Hickory Bacon Flavor
Overview:
Strellalab’s 120-count hickory-bacon chews promise fast, hemp-powered relaxation for dogs rattled by fireworks, separation, or travel.
What Makes It Stand Out:
The melatonin-hemp duo is rare in the sub-$25 space, and the soft, aromatic bacon bite eliminates pill-wrap games.
Value for Money:
At $0.21 per chew you get 60 doses for a 40-lb dog—cheaper than a single vet sedative and half the price of comparable hemp-melatonin combos.
Strengths and Weaknesses:
+ Visible mellowing within 30–45 min for most pups
+ No corn, soy, or synthetic colors
+ Re-sealable tub stays fresh for months
– Hickory scent is strong; some dogs turn up their noses
– Not for pregnant or epileptic dogs (melatonin)
– Hemp level is moderate, so giant breeds may need several chews
Bottom Line:
A budget-friendly, bacon-flavored chill-pill that works for everyday stressors; ideal for medium dogs and noise-phobic pups.
7. Heavenly Hounds Peanut Butter Chews – Anxiety Relief for Dogs – Natural Ingredients – No Hemp Calming Snacks, 2 Oz – Pack of 4
Overview:
Heavenly Hounds offers four 2-oz peanut-butter squares free of hemp, relying instead on passion-flower, valerian, and B-vitamins to take the edge off anxious dogs.
What Makes It Stand Out:
Single-serve packaging means no guessing, no fridge-door tub, and zero hemp for owners who worry about cannabis associations.
Value for Money:
$5 per 2-oz square feels steep, but each square calms a 50-lb dog for 4–6 h—cheaper than daycare, pricier than bulk chews.
Strengths and Weaknesses:
+ USA-made, wheat/soy/corn-free
+ Soft texture seniors can gum
+ Refrigerate leftovers—no spoilage waste
– Only four doses; multi-dog households burn through fast
– 5% of dogs see no effect (company admits)
– Can loosen stools; start with half a square
Bottom Line:
Perfect “hemp-free” travel companion for occasional stress; stock up if you own more than one pup or deal with daily anxiety.
8. Hemp Calming Chews for Dogs Anxiety – Dog Calming Treats with Melatonin, Valerian Root, Chamomile Extract & Vitamin B Complex – Canine Chews for Vet Visits, Grooming, Travel, Thunderstorms, Fireworks
Overview:
Chewia’s 120-count tub layers hemp, valerian, chamomile, B-complex, and melatonin into a turkey-flavored chew marketed for hyperactive, destructive, or noise-phobic dogs.
What Makes It Stand Out:
The brand pushes “focus and behavior” rather than mere sedation—useful for training classes or agility trials.
Value for Money:
$21.99 breaks down to $0.18 per chew, undercutting most hemp-melatonin formulas while adding cognitive-support vitamins.
Strengths and Weaknesses:
+ Turkey aroma entices picky eaters
+ Noticeable calm within 20–30 min without drowsiness
+ Made in FDA-registered facility
– Square shape is firm; tiny dogs may need breaking
– Not poultry-free for allergy dogs
– Melatonin can flatten energy all day if overdosed
Bottom Line:
A well-balanced, training-friendly calmer that sharpens attention while muting stress; monitor dose to avoid nap-time overkill.
9. Calming Hemp Treats for Dogs Made in USA Organic Hemp Natural Separation Aid Helps Barking, Chewing, Thunder, Fireworks, Aggressive Behavior Soothing Stress Relief Natural Relaxation 120 Chews
Overview:
LegitPet’s 120 duck-flavored chews lean on organic hemp, chamomile, and valerian to curb barking, chewing, and storm terror without corn, soy, or artificial fillers.
What Makes It Stand Out:
“Organic hemp” badge plus duck protein gives owners a clean-label option for dogs with chicken or beef allergies.
Value for Money:
$23.99 equates to $0.20 per chew—mid-pack pricing, but you’re paying for certified organic botanicals.
Strengths and Weaknesses:
+ Soft texture; can hide pills inside
+ No added sugar or salt
+ Works for giant breeds at double dose without GI upset
– Duck smell is pungent; hands need washing
– Tub lid can crack on shipment
– Takes 45–60 min for peak effect—plan ahead
Bottom Line:
A clean, hypoallergenic relaxer worth the slight premium for sensitive or allergy-prone dogs; just open the windows after serving.
10. Hemp Calming Chews for Dogs 180Ct – Dog Calming Chews – Anxiety Relief Treats and Bites for Dogs – Dog Supplements for Separation, Thunderstorms, Stress, Barking, Promote Relaxation – Chicken Flavor
Overview:
This 180-count chicken chew combines hemp, chamomile, ashwagandha, L-theanine, L-tryptophan, and ginger to deliver all-day calm for puppies through seniors.
What Makes It Stand Out:
Highest count (180) and lowest per-chew price ($0.13) while still being grain-free and vet-recommended—rare economies of scale.
Value for Money:
A 40-lb dog gets 90 doses per tub, costing roughly 26 ¢ per day—less than a dental chew and far below prescription anxiolytics.
Strengths and Weaknesses:
+ Ashwagandha & ginger ease both stress and stomach
+ Effects last 6–8 h for most dogs
+ 90-day money-back guarantee
– Chicken flavor can crumble in shipment; check for dust
– Large tubs risk moisture if not re-sealed tight
– Not for dogs on SSRIs (L-tryptophan interaction)
Bottom Line:
The best bulk buy for multi-dog homes or chronic anxiety; seal tight, mind drug interactions, and enjoy months of serenity for under twenty-five bucks.
Why Mushrooms and CBD Make a Power Couple for Dogs
Cannabinoids and medicinal mushrooms share a common super-power: they both modulate the endocannabinoid and immune systems, creating a synergy that can ease anxiety, inflammation, and cognitive decline more gently than pharmaceuticals. CBD quiets overactive nerves; mushrooms rebuild and regulate. Together they form a “whole-dog” approach that works on mood, mobility, and immunity at the same time.
The Endocannabinoid System in Canines: A Quick Refresher
Dogs have more CB1 receptors in their hindbrains than humans, which is why THC toxicity is dangerous for them—but also why non-intoxicating, hemp-derived CBD is so effective. A well-formulated chew delivers cannabinoids that bind to CB1/CB2 sites, dialing down pain perception and allergic flare-ups without psychoactive side effects.
Functional Fungi 101: Which Mushrooms Matter
Beta-Glucans and Triterpenes: The Active Alphabet
These long-chain polysaccharides and bitter compounds are the real protagonists. Beta-glucans prime innate immunity; triterpenes modulate liver enzymes and cortisol. Look for treats that guarantee at least 20 % beta-glucan content verified by third-party labs.
Reishi: The Calming “Mushroom of Immortality”
Reishi’s triterpenes interact with GABA receptors, promoting deeper REM cycles—crucial for senior dogs who pace at 2 a.m.
Lion’s Mane: Cognitive Support for Senior Pups
Hericenones and erinacines stimulate nerve growth factor (NGF), shown in pilot studies to delay canine cognitive dysfunction.
Turkey Tail: Gut-Immune Modulation Leader
Rich in PSP & PSK peptides, turkey tail acts as a prebiotic for beneficial gut flora while simultaneously up-regulating natural killer cells.
Cordyceps: Natural Energizer Without the Jitters
Increases ATP production via cordycepin, giving working or athletic dogs a stamina boost minus caffeine-like overstimulation.
Chaga: Antioxidant Heavy-Hitter
ORAC values off the charts—ideal for breeds predisposed to oxidative stress such as brachycephalic seniors.
Shiitake: Palatability Plus Cardiovascular Perks
Lentinan supports healthy cholesterol levels and lends an umami flavor most dogs find irresistible.
Full-Spectrum vs. Broad-Spectrum vs. Isolate: CBD Vocabulary You Need
Full-spectrum retains <0.3 % THC (legal federally) plus minor cannabinoids and terpenes for the entourage effect. Broad-spectrum removes THC entirely but keeps other hemp compounds—perfect for households with drug-screening concerns. Isolate is 99 % pure CBD; it’s flavorless but lacks synergistic partners.
Decoding the Certificate of Analysis (COA): Mushroom & Hemp Edition
A reputable COA will list not only CBD and THC percentages but also beta-glucan assay, heavy-metal panel, pesticide screen, and microbial count. Cross-check lot numbers on the bag with the lab report online; if they don’t match, walk away.
Potency Math: How Many Milligrams Does Your Dog Actually Need?
Start with 0.2 mg of CBD per pound of body weight twice daily for wellness; move up to 0.5 mg/lb for targeted issues like storm phobia. Mushroom dosage is weight-agnostic—look for 500 mg of dual-exact fruiting-body blend per chew for a 50-lb dog, then scale proportionally.
Delivery Format: Soft Chews, Crunchy Biscuits, or Powder Toppers?
Soft chews win on palatability and precise dosing; crunchy biscuits can be baked at temperatures that degrade cannabinoids; powders let you customize but risk inconsistent scoops. For picky eaters, a soft chew with natural bacon or peanut-butter flavor typically scores highest.
Carrier Oils & Absorption: Why MCT From Coconut Outperforms Hemp Seed
MCT oil increases CBD bioavailability by 3–4× compared to treats using only hemp-seed oil. Bonus: it supplies rapid ketone energy for cognitive sharpness.
Organic Cultivation, Dual Extraction, and Fruiting Body Integrity
Mushrooms grown on sorghum or oat substrate can absorb grain sugars, diluting potency. Seek certified-organic fruiting bodies that are hot-water AND alcohol extracted—this pulls both water-soluble beta-glucans and alcohol-soluble triterpenes.
Allergen Alerts: Chicken, Grain, and Novel Protein Considerations
Novel proteins like rabbit or vegan pumpkin are ideal for elimination-diet dogs. Grain-inclusive chews can contain hidden mycotoxins; grain-free isn’t always better if legumes replace carbs—dilated cardiomyopathy risk. Scan for “single-protein, single-carb” formulas if your pup has itchy ears.
Reading Between the Marketing Lines: “Vet-Formulated” vs. “Vet-Approved”
“Vet-formulated” means a licensed DVM helped design the recipe; “vet-approved” may only indicate a veterinarian somewhere said “sounds fine.” Look for NASC (National Animal Supplement Council) quality seals and transparent advisory boards.
Traveling and Boarding: Hemp Laws Across State Lines
Hemp is federally legal, but some states (think Idaho and South Dakota) treat any CBD product like marijuana. Carry a printed COA and keep treats in original packaging. Airline rules vary—TSA allows hemp but confirm with the carrier before you stuff chews in a carry-on.
Side-Effect Watchlist: When Less Is More
Transient sedation, loose stool, or slight drop in blood pressure can occur. Reduce dose by 50 % if your dog becomes wobbly. Mushrooms can trigger digestive upset in histamine-sensitive dogs—introduce over five days.
Long-Term Wellness Protocols: Cycling, Stacking, and Rotation
Give CBD daily but rotate mushroom blends every 8–12 weeks to avoid receptor down-regulation. Example: reishi-cordyceps for winter immunity, lion’s mane-turkey tail for spring allergy season.
Budgeting for Quality: Cost Per Active Milligram
Divide package price by total CBD + total beta-glucan milligrams to get true cost. Premium treats land around $0.18–$0.25 per combined active mg; anything cheaper usually cuts corners on extraction or lab testing.
Sustainability & Ethics: From Mycelium to Packaging
Compostable pouches, mushroom substrates up-cycled from coffee grounds, and hemp grown with regenerative farming lower your dog’s carbon paw-print. Support brands that publish annual impact reports.
DIY Safety: Why Kitchen Extraction Is a Bad Idea
Mushrooms need precise temperature, pressure, and solvent ratios to isolate actives without toxins. Home ethanol baths risk residual solvents; skip the Pinterest recipes and trust certified labs.
Frequently Asked Questions
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Will CBD mushroom treats get my dog high?
No. Hemp-derived CBD contains <0.3 % THC, and functional mushrooms contain no psychoactive compounds—only calming, adaptogenic benefits. -
How soon will I see results for my dog’s joint stiffness?
Most owners notice increased willingness to climb stairs within 3–7 days; optimal anti-inflammatory effect peaks after 2–3 weeks of consistent dosing. -
Can I give these treats alongside prescription NSAIDs?
Yes, but inform your veterinarian. CBD may potentiate NSAIDs, allowing lower drug doses—never discontinue prescribed meds without professional guidance. -
Are there breed-specific concerns for CBD or mushrooms?
Herding breeds with MDR1 gene mutations metabolize some drugs differently; CBD is safe, but start at the low end of the dose range and monitor. -
Do mushroom beta-glucans interfere with allergy shots or vaccines?
No evidence shows interference; in fact, turkey tail can enhance vaccine titers by stimulating antibody production. -
How do I store CBD mushroom chews to keep them potent?
Seal tightly, store below 75 °F, and use within 90 days of opening. Refrigeration extends shelf life but may harden soft chews—let sit at room temp 10 min before serving. -
My dog is on phenobarbital for seizures; is CBD safe?
Studies report reduced seizure frequency when CBD is added, but blood-level monitoring is crucial. Adjust phenobarbital only under veterinary supervision. -
Can puppies eat these treats?
Vets generally recommend waiting until 6 months of age when the endocannabinoid system matures; choose a lower-potency puppy-specific chew if available. -
What’s the difference between mycelium and fruiting body, and why should I care?
Mycelium is the root-like network grown on grain; it contains lower actives and up to 60 % filler starch. Fruiting body is the actual mushroom cap & stem—higher in beta-glucans. -
Will my dog fail a “drug test” at a boarding facility?
Standard canine urine screens test for THC metabolites, not CBD. Hemp treats with non-detectable THC will not trigger a positive result—keep that COA handy just in case.