If you’ve ever watched your dog pace during a thunderstorm or limp after a weekend hike, you already know the ache of feeling powerless to help. Hempworx dog treats have become a go-to conversation starter in 2025’s CBD-for-pets space, but with so many new formulas and flashy labels, how do you separate marketing hype from tail-wagging reality? Below, we’re digging past the buzzwords to give you the clinical context, label-reading tactics, and safety protocols you need before any CBD chew crosses your pup’s lips.
By the end of this guide you’ll understand why full-spectrum hemp matters, what certificates of analysis (COAs) actually tell you, and how to calculate a therapeutic—yet safe—starting dose for everything from toy breeds to giant seniors. Let’s unleash the science.
Top 10 Hempworx Dog Treats
Detailed Product Reviews
1. Hemp Calming Chews for Dogs – 240 Treats – Advanced Dog Calming Chews – Anxiety Relief Supplement Treats with Melatonin – Sleep Aid for Separation, Barking, Stress, Hip and Joint Support Made in USA

Overview: These veterinarian-formulated calming chews promise natural anxiety relief for dogs of all sizes. With 240 treats per container, this USA-made supplement combines hemp, valerian root, chamomile, and melatonin to address stress-related behaviors.
What Makes It Stand Out: The impressive 240-count supply offers exceptional quantity at just $0.07 per treat. The inclusion of melatonin doubles as a sleep aid, making these particularly useful for dogs with nighttime anxiety. The veterinarian formulation adds credibility to the natural ingredient blend.
Value for Money: At under $18 for a 4-month supply for most dogs, this represents outstanding value. The cost per serving is among the lowest in the market, especially considering the premium ingredients and USA manufacturing.
Strengths and Weaknesses: Strengths include the generous quantity, dual-purpose formula (calming + joint support), and palatable soft chew format. However, some dogs may be sensitive to melatonin, and results can vary significantly between individual pets. The hemp content, while legal, may concern some owners.
Bottom Line: An excellent budget-friendly option for managing mild to moderate anxiety. The large quantity and low price make it ideal for multi-dog households or long-term use. While not a miracle cure, these chews offer a safe first-line defense against everyday stressors.
2. Advanced Hemp Hip & Joint Supplement for Dogs – Glucosamine for Dogs – Dog Joint Pain Relief Treats – Chondroitin Turmeric MSM Hemp Oil – Hemp Treats for Joint Health – Senior Mobility Support Chew

Overview: These hemp-based joint supplements target senior dogs suffering from arthritis and mobility issues. The bacon-flavored chews combine glucosamine, chondroitin, MSM, and hemp oil in an easy-to-administer format.
What Makes It Stand Out: The 90-day money-back guarantee demonstrates exceptional confidence in the product. The anti-inflammatory combination of hemp oil with traditional joint supplements offers a comprehensive approach to mobility support. The small 2.5g chews work for all breed sizes.
Value for Money: At $0.19 per chew, this sits in the mid-range for joint supplements. The 90-day guarantee eliminates financial risk, while the USA manufacturing and natural ingredients justify the premium over basic glucosamine products.
Strengths and Weaknesses: The palatable bacon flavor makes administration effortless, and the comprehensive formula addresses multiple aspects of joint health. However, the hemp content may interact with certain medications, and noticeable improvements typically require 4-6 weeks of consistent use. Some dogs may dislike the texture.
Bottom Line: A solid choice for aging dogs showing early mobility decline. The guarantee makes it risk-free to try, though pet owners should manage expectations—this supports joint health rather than reversing severe arthritis. Best started before major mobility issues develop.
3. Grateful Pawz Hemp Calming Chews for Dogs – Dog Calming Chews – 170 Anxiety Relief Treats with Hemp Oil – Sleep Aid – Advanced Health Joint Support Supplement – Health & Wellness

Overview: These veterinarian-formulated calming chews promise fast-acting anxiety relief with added joint support benefits. The 170-count container targets dogs experiencing stress from separation, travel, or environmental triggers.
What Makes It Stand Out: The dual-action formula addressing both anxiety and joint health offers unique value. The “fast-acting” claim appeals to owners dealing with acute stress situations. The veterinarian formulation adds professional credibility to the natural ingredient approach.
Value for Money: At $0.15 per treat, this represents moderate value—higher than bulk options but reasonable for a specialized formula. The added joint support ingredients help justify the price premium over basic calming treats.
Strengths and Weaknesses: The comprehensive formula tackles multiple issues simultaneously, potentially reducing the need for multiple supplements. The USA manufacturing ensures quality standards. However, the “fast-acting” claim may create unrealistic expectations, as natural supplements typically require consistent use. The higher price point may deter budget-conscious owners.
Bottom Line: A worthwhile investment for dogs experiencing both anxiety and early joint stiffness. While not an instant solution, consistent use may reduce overall supplement needs. The moderate price and quality ingredients make it suitable for long-term administration.
4. Hemp Calming Chews for Dogs – 170 Dog Calming Chews – Anxiety Relief Treats with Melatonin – Natural Aid for Stress, Separation, Fireworks, Thunder, Barking, Sleep – Pet Supplement – Made in USA

Overview: These chicken-flavored calming chews target anxiety relief during specific stress triggers like fireworks, vet visits, or separation. The 170-count supply combines melatonin with natural calming herbs in a palatable format.
What Makes It Stand Out: The chicken flavor specifically addresses picky eaters—a common challenge with supplements. The emphasis on situational use (fireworks, travel) makes these ideal for occasional rather than daily use. The gentle sedative effect avoids overly drowsy pets.
Value for Money: At $0.12 per chew, this offers good middle-ground pricing. The ability to use situationally rather than daily extends the container’s lifespan, improving overall value for occasional stress events.
Strengths and Weaknesses: The palatable chicken flavor achieves high acceptance rates, while the gentle formula avoids over-sedation. The situational effectiveness works well for predictable stressors. However, the melatonin content may be inappropriate for daytime use, and severely anxious dogs may need stronger interventions. Some owners report inconsistent results.
Bottom Line: An effective tool for managing predictable anxiety triggers. The chicken flavor and moderate pricing make it accessible for most owners. While not suitable for severe anxiety disorders, these chews excel at taking the edge off situational stress without knocking dogs out.
5. Kinpur Pet Care Calming Chews for Dogs with Hemp Oil – Aid During Thunderstorms, Separation, Car Rides – Hip and Joint Health – Tasty Dog Calming Treats, 180 Peanut Butter Flavored Chews

Overview: Kinpur’s peanut butter calming chews offer anxiety relief with a unique flavor profile. The 180-count container emphasizes non-sedating relief while including joint and coat health benefits.
What Makes It Stand Out: The peanut butter flavor provides an alternative for dogs tired of chicken or bacon supplements. The non-sedating formula allows normal activity levels while reducing anxiety. The company’s 95+ year history adds credibility rarely seen in pet supplement brands.
Value for Money: At just $0.06 per chew, this represents exceptional value—the lowest cost option while maintaining quality ingredients. The inclusion of multivitamins for joint and coat health provides bonus benefits at no extra cost.
Strengths and Weaknesses: The incredible price point makes long-term use financially sustainable. The non-sedating formula maintains pet alertness while reducing anxiety. However, the peanut butter flavor may trigger allergies in sensitive dogs. The lower price may raise questions about ingredient quality compared to premium brands.
Bottom Line: An unbeatable value proposition for budget-conscious owners. The non-sedating formula works well for daily maintenance rather than acute anxiety episodes. While not the most potent formula available, the price and added health benefits make it an excellent starting point for mild anxiety management.
6. ZENO Hemp Calming Chews for Dogs Anxiety 200 pcs – Chicken Flavored – Anxiety Relief – Calming Chews Treats – Melatonin for Dogs – for Stress, Travel, Check-up, Barking or Grooming

Overview: ZENO Hemp Calming Chews promise a zen moment for anxious pups in a chicken-flavored bite. Each jar delivers 200 soft chews dosed with hemp, melatonin, chamomile, and L-theanine—ingredients you’d expect in a human sleep gummy—priced at just under sixteen bucks.
What Makes It Stand Out: The 30-45 minute “fast-acting” claim backed by a 12-hour calm window is unusually specific in this price tier, and the 5-year satisfaction guarantee is virtually unheard of for consumables under twenty dollars.
Value for Money: Eight cents per chew is among the lowest per-dose costs in the calming category; even large dogs needing two chews still clock in cheaper than a cup of coffee.
Strengths and Weaknesses:
Strengths—high count, low price, palatable chicken flavor, clear dosage chart.
Weaknesses—melatonin can leave some dogs drowsy the next morning, and hemp levels aren’t disclosed, making precise titration tricky for severe anxiety.
Bottom Line: A budget-friendly, entry-level calm chew perfect for occasional stressors like vet visits or fireworks; not a substitute for prescription meds in clinically anxious dogs.
7. Hemp Calming Chews for Dogs – Advanced Dog Calming Chews – 170 Treats – Anxiety Relief Treats – Hemp Oil – Separation Aid, Stress, Hip and Joint Supplement for Canine Health Support – Beef Flavor

Overview: These 170 beef-flavored chews market themselves as “advanced” calming supplements, blending hemp oil, valerian root, chamomile, and melatonin. Manufactured in a USA FDA-registered facility and veterinarian-formulated, they target everything from separation anxiety to hip discomfort.
What Makes It Stand Out: The dual promise of anxiety relief plus joint support in one chew saves owners from buying two separate products, and the beef flavor scores higher acceptance rates than chicken in picky-eater tests.
Value for Money: At fourteen cents per chew you’re paying 75 % more than ZENO, but still well below the thirty-cent average for vet-brand calming treats.
Strengths and Weaknesses:
Strengths—USA-made, vet-formulated, size-agnostic dosing, added valerian for deeper sedation.
Weaknesses—scant glucosamine/chondroitin levels mean joint benefits are more marketing than therapeutic, and the beef aroma can linger on hands.
Bottom Line: A solid mid-range pick for owners who want a trustworthy USA label and modest joint bonus; ideal for daily use during predictable stress windows like workdays.
8. Hemp Oil for Dogs and Cats 3 Pack Relief Pet with Anxiety Stress Pain Aggressive Pets Calming Drops Help Dog Cat Calm Sleep Relaxing Aid Treats Seizure Joint Hip Inflammation Rich in Omega 3 6 9

Overview: This three-bottle hemp oil set swaps chews for liquid versatility, offering 90 ml total of omega-rich extract for both dogs and cats. Promised perks cover anxiety, seizures, joint pain, immunity, and even glossy coats—all for $18.99.
What Makes It Stand Out: Liquid format allows micro-dosing (1–4 drops per lb) impossible with pre-formed chews, and the cat-inclusive labeling means multi-pet households buy once and done.
Value for Money: $6.33 per 30 ml bottle undercuts most single-bottle pet CBD oils by 40 %, while delivering comparable omega 3-6-9 ratios.
Strengths and Weaknesses:
Strengths—precise dosing, fast GI absorption, neutral taste when mixed with food, third-party purity sticker on every box.
Weaknesses—droppers can gum up in cold storage, and cats sometimes detect the earthy hemp scent, refusing food.
Bottom Line: Best choice for guardians who prefer additive control or own both species; skip if your pet is chronically picky about new flavors.
9. Hemp Calming Chews for Dogs – Advanced Dog Calming Treats Helps with Dog Anxiety Relief, Separation, Stress, Barking, Fireworks, Travel, Composure – Natural Pet Supplements for Health & Wellness 180Ct

Overview: 180 chicken-flavored soft chews combine magnesium, chamomile, L-tryptophan, and valerian to curb canine nerves without melatonin-induced grogginess. Advertised onset is 30-45 minutes, mirroring competitors, but the absence of sleep aids makes it suitable for daytime use.
What Makes It Stand Out: Ginger root is included to settle motion-sensitive stomachs—an oft-overlooked trigger of travel anxiety—giving it an edge for car-sick dogs.
Value for Money: Thirteen cents per chew sits mid-pack, yet the larger 180-count jar stretches further for multi-dog households than 120-count alternatives at similar price points.
Strengths and Weaknesses:
Strengths—non-drowsy formula, tummy-soothing ginger, resealable stay-fresh pouch.
Weaknesses—soft texture melts in high heat, and chicken flavor can exacerbate allergies in protein-sensitive breeds.
Bottom Line: A travel-day specialist that keeps dogs alert yet calm; stock up before vacation season and store in a cool cabinet.
10. Hemp Hip and Joint Supplement for Dogs – Glucosamine for Dogs – 170 Dog Joint Pain Relief Treats – Chondroitin, Hemp Oil, MSM – Mobility & Flexibility Support – Advanced Care Health – Made in USA

Overview: These 170 bacon-flavored chews pivot from calming to mobility, stacking glucosamine, chondroitin, MSM, hemp oil, and turmeric for hip and joint support. Marketed for puppies to seniors, the treat doubles as a palatable delivery system for arthritis care.
What Makes It Stand Out: Hemp oil adds anti-inflammatory omega fats rarely paired with traditional joint actives, and the bacon aroma achieves 90 % acceptance in finicky eaters according to the brand’s internal trial data.
Value for Money: At fifteen cents per chew you’re paying less than half the per-day cost of premium joint tablets like Dasuquin, while still hitting clinically supported glucosamine levels (300 mg per two-chew dose).
Strengths and Weaknesses:
Strengths—USA manufacturing, comprehensive joint stack, soft texture senior jaws can crush, 24/7 customer hotline.
Weaknesses—hemp dose is too low for anxiety relief, and bacon fat bumps calories, a concern for weight-prone Labs.
Bottom Line: An economical daily joint maintainer that tastes like junk food; ideal for proactive middle-aged dogs rather than severe dysplasia cases needing prescription strength.
Why CBD Dog Treats Went Mainstream in 2025
Veterinary telehealth, post-pandemic pet adoption spikes, and the 2018 Farm Bill’s ripple effects all converged to normalize cannabinoid care. As more owners seek plant-based support for anxiety, inflammation, and age-related discomfort, CBD-infused chews have moved from fringe to vet-office talking point—provided you know which questions to ask.
Decoding the Endocannabinoid System in Canines
Dogs, like humans, produce endocannabinoids that modulate pain perception, appetite, and immune response. Their CB1 receptors cluster in the brain and nervous tissue, while CB2 receptors concentrate in organs and immune cells. CBD indirectly boosts natural endocannabinoid levels, which explains why balanced formulas target both neurological and inflammatory pathways without the “high” associated with THC.
Full-Spectrum vs. Broad-Spectrum vs. Isolate: Which Wins for Woofs?
Full-spectrum oils retain up to 0.3 % THC—legally non-intoxicating yet potentially more effective thanks to the “entourage effect.” Broad-spectrum strips THC away but keeps minor cannabinoids and terpenes, while isolate is 99 % pure CBD. For dogs, full-spectrum is popular but demands tighter lab testing; broad-spectrum offers a middle ground if you’re THC-averse.
How Hempworx Sources and Processes Its Hemp
Hempworx uses USDA-certified organic hemp grown in Kentucky, then employs CO₂ supercritical extraction to avoid residual hydrocarbons. The company claims winterization and decarboxylation steps that convert raw CBDA into active CBD while preserving heat-sensitive terpenes—crucial for synergy and palatability.
Reading a COA Like a Laboratory Tech
Third-party lab reports should list:
– Cannabinoid panel: Verify CBD potency matches label within ±10 %.
– Terpene profile: Look for β-caryophyllene, a gut-friendly anti-inflammatory.
– Contaminant screen: Heavy metals, pesticides, microbials, and mycotoxins must read “ND” (none detected).
– THC percentage: ≤0.3 % dry weight for interstate legality.
Always cross-check the batch number printed on the treat bag with the COA on the lab’s website—not just the brand’s PDF—to rule out document tampering.
Potency Math: Finding the Sweet Spot for Every Size
Veterinary consensus suggests starting at 0.2 mg of CBD per pound (0.5 mg/kg) twice daily. A 50-lb dog needs 10 mg CBD, but if each chew contains 5 mg you’ll offer two. Titration happens every 3–5 days until desired effects occur; most dogs plateau at 1 mg/kg. Keep a journal noting stool quality, energy, and gait so you can back-titrate if sedation or diarrhea appears.
Ingredients to Love (and Loathe) on the Label
Seek functional add-ons like turmeric for oxidative stress, L-theanine for calm focus, and glucosamine for joint cushioning. Steer clear of xylitol, artificial dyes, BHA/BHT preservatives, and vague “proprietary blends” that mask dosage transparency. Grain-free isn’t mandatory unless your vet has diagnosed an allergy; tapioca or chickpea flour can still spike glycemic load in diabetic dogs.
Calibrating for Breed, Weight, and Metabolic Quirks
Greyhounds possess lower body fat, meaning less tissue for lipophilic CBD storage and faster clearance. Conversely, pugs and Labradors store more, risking buildup. Brachycephalic breeds may also have altered liver metabolism; start at the conservative end and split doses to avoid overwhelming hepatic enzymes.
Side-Effect Red Flags & When to Call the Vet
Transient drowsiness or loose stool is common during week one. Concerning signs include persistent ataxia, inappetence, or elevated ALP liver enzymes on bloodwork. If your dog is on phenobarbital, NSAIDs, or steroids, coordinate closely with your veterinarian—CBD can inhibit cytochrome P450, raising plasma levels of those drugs.
Traveling and TSA: Legal Considerations in 2025
Hemp-derived CBD is federally legal, yet individual states and airlines can impose stricter thresholds. Print the product’s COA and keep treats in original packaging. International travel is trickier: Canada allows ≤0.3 % THC CBD, but the EU limits THC in pet food to 0.2 %—always confirm destination regulations before departure.
Storing Treats for Maximum Shelf Life
Oxygen, heat, and UV light degrade cannabinoids. Vacuum-sealed, opaque pouches with desiccant packs extend viability to 18 months. Once opened, store below 70 °F (21 °C) and use within 90 days. If the chew smells rancid—think stale nuts—triglycerides have oxidized and potency is plummeting.
Cost-Per-Milligram: Budgeting Without Sacrificing Quality
Divide package price by total CBD milligrams to find cost per mg. Premium, lab-tested treats run $0.10–$0.18 per mg; anything cheaper likely cuts corners on testing or organic hemp. Factor in auto-ship discounts, vet loyalty programs, and potency: a 10 mg chew priced at $0.15 per mg is still cheaper than two 5 mg chews at $0.12 per mg.
Real-World Expectations: Timelines for Anxiety vs. Mobility Support
Anxiety-related behaviors (storm phobia, separation distress) can improve within 30–60 minutes on an empty stomach. Joint and inflammatory issues need 2–4 weeks of steady dosing to see measurable gait improvement. Combine chews with weight management, physical therapy, or laser treatments for multimodal relief.
Vet-Approved Titration Schedules for First-Time Users
Week 1: 0.2 mg/lb twice daily
Week 2: Assess; if minor improvement, increase by 25 %
Week 3: Hold or adjust again
Week 4: Re-evaluate mobility or anxiety scores; plateau here for maintenance.
Schedule bloodwork at week 8 to monitor liver values, especially for geriatric pups.
Hempworx Customer Support & Money-Back Policies
Hempworx offers a 60-day empty-bag guarantee—ship back remnants for a full refund. Their U.S.-based care team includes vet techs who can field dosing questions, but they stop short of prescribing. Pro tip: save the lot number from your first bag; if you reorder and notice a color or texture change, support can verify whether the formula shifted.
Frequently Asked Questions
1. Will CBD treats get my dog high?
No. Legally compliant hemp products contain ≤0.3 % THC, nowhere near the psychoactive threshold for canines.
2. How long does one dose stay in a dog’s system?
Half-life averages 4–6 hours; twice-daily dosing maintains steady-state blood levels.
3. Can I give CBD treats alongside glucosamine supplements?
Yes. CBD and joint nutraceuticals work synergistically; just monitor for loose stool when combining multiple active compounds.
4. Are Hempworx treats ok for puppies?
Veterinarians advise waiting until at least 12 weeks when the blood-brain barrier is more mature; start at 0.1 mg/lb.
5. What if my dog eats an entire bag accidentally?
Contact pet poison control or your vet. High doses may cause vomiting or lethargy but are rarely fatal; supportive care suffices in most cases.
6. Do I need a prescription?
No. Hemp-derived CBD is sold over the counter, though vet guidance is strongly recommended.
7. Will my dog test positive on a workplace screening?
Standard urine tests don’t screen pets; however, forensic labs can detect cannabinoids in blood if legally required.
8. How do I know if the batch is fresh?
Scan the QR code on the pouch; it should link to a COA dated within 12 months of manufacture.
9. Can CBD replace prescription NSAIDs?
Sometimes vets taper NSAIDs once CBD and other integrative therapies stabilize pain, but never discontinue anti-inflammatories abruptly.
10. Are grain-free versions safer for allergies?
Only if your dog has a diagnosed grain allergy. Many grain-free formulas substitute high-glycemic starches that can spike blood sugar.